SCHEMBL30759625

SCHEMBL30759625

COc1cc2c(cc1-c1cncc(C(N)=O)c1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cc(Cl)cc(Cl)c1)CC2

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PDE7A Q13946 1/20 0.36
▸ PDE3A Q14432 1/20 0.36
▸ PDE10A Q9Y233 1/20 0.36
▸ RAD52 P43351 1/20 0.35
▸ IKBKB O14920 10/20 0.35
▸ CCNA2 P20248 3/20 0.33
▸ CDK2 P24941 3/20 0.33
▸ CCNA1 P78396 3/20 0.33
▸ ALPL P05186 1/20 0.33
▸ F10 P00742 2/20 0.32
▸ CHUK O15111 1/20 0.31
▸ CYP11B1 P15538 1/20 0.31
▸ CYP11B2 P19099 1/20 0.31
▸ MKNK1 Q9BUB5 1/20 0.31
▸ MKNK2 Q9HBH9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27119776 1.00 PDE7A (0.36) PDE7APDE3APDE10ARAD52IKBKB
SCHEMBL30759608 0.94 PDE7A (0.35) PDE7APDE3APDE10AIKBKBCCNA2
SCHEMBL27118994 0.94 PDE7A (0.35) PDE7APDE3APDE10AIKBKBCCNA2
SCHEMBL27120317 0.93 RAD52 (0.34) PDE7APDE3APDE10ARAD52IKBKB
SCHEMBL27122870 0.93 RAD52 (0.36) RAD52IKBKBCCNA2CDK2CCNA1
SCHEMBL27122203 0.92 RAD52 (0.38) PDE7APDE3APDE10ARAD52IKBKB
SCHEMBL27122174 0.90 RAD52 (0.36) RAD52IKBKBCCNA2CDK2CCNA1
SCHEMBL27120632 0.90 RAD52 (0.39) RAD52IKBKBCCNA2CDK2CCNA1
SCHEMBL27122153 0.90 RAD52 (0.40) RAD52IKBKBCCNA2CDK2CCNA1
SCHEMBL27120639 0.89 CYP11B2 (0.36) RAD52IKBKBCCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR PDE7A 400/4885PDE3A 386/4885PDE10A 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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