SCHEMBL30759569

SCHEMBL30759569

COc1cc2c(cc1-c1cncc(C#N)c1)-c1c(c(C(=O)N3CCOCC3(C)C)nn1-c1cc(Cl)cc(Cl)c1)SC2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 3/20 0.36
▸ PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27118044 1.00 GRM5 (0.36) GRM5PTGS2
SCHEMBL27118045 0.90 GRM5 (0.33) GRM5PTGS2
SCHEMBL30759535 0.89 GRM5 (0.38) GRM5
SCHEMBL27118811 0.89 GRM5 (0.38) GRM5
SCHEMBL30759686 0.89 GRM5 (0.37) GRM5
SCHEMBL27119422 0.89 GRM5 (0.37) GRM5
SCHEMBL27152593 0.88 GRM5 (0.37) GRM5
SCHEMBL31758931 0.88 GRM5 (0.37) GRM5
SCHEMBL30759519 0.85 GRM5 (0.36) GRM5PTGS2
SCHEMBL27118043 0.85 GRM5 (0.36) GRM5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR GRM5 222/4885PTGS2 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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