SCHEMBL30759571

SCHEMBL30759571

COc1cc2c(cc1Br)-c1c(c(C(=O)N3CCOCC3(C)C)nn1-c1cc(Cl)cc(Cl)c1)OC2

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 3/20 0.38
▸ GLA P06280 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ PIK3CD O00329 1/20 0.31
▸ PIK3R2 O00459 1/20 0.31
▸ PIK3CA P42336 1/20 0.31
▸ PIK3CB P42338 1/20 0.31
▸ PIK3CG P48736 1/20 0.31
▸ PIK3R5 Q8WYR1 1/20 0.31
▸ PIK3R3 Q92569 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27117858 1.00 GRM5 (0.38) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL31236983 0.94 GRM5 (0.38) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL27117920 0.88 GRM5 (0.37) GRM5PIK3CDPIK3R2PIK3CAPIK3CB
SCHEMBL27118703 0.88 GRM5 (0.38) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL30759592 0.87 GRM5 (0.38) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL27119377 0.87 GRM5 (0.38) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL30759519 0.85 GRM5 (0.36) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL27118043 0.85 GRM5 (0.36) GRM5GLAKMT2APIK3CDPIK3R2
SCHEMBL31758931 0.85 GRM5 (0.37) GRM5
SCHEMBL27152593 0.85 GRM5 (0.37) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR GRM5 222/4885GLA 3157/4885KMT2A 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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