Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.51 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 7/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27091783 | 0.81 | CRBN (0.55) | CRBNDDB1ARKDM4EALDH1A1 | |
| SCHEMBL23551629 | 0.80 | KDM4E (0.49) | CRBNDDB1ARPDE3BPDE3A | |
| SCHEMBL31444174 | 0.78 | CRBN (0.55) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL31437047 | 0.78 | DDB1 (0.46) | CRBNDDB1NOTUM | |
| SCHEMBL15766789 | 0.74 | DDB1 (0.64) | CRBNDDB1ARKDM4EALDH1A1 | |
| SCHEMBL21995598 | 0.74 | CRBN (0.71) | CRBNDDB1KDM4EALDH1A1HPGD | |
| SCHEMBL26641696 | 0.73 | HTR3E (0.43) | CRBNDDB1ARALDH1A1 | |
| SCHEMBL25667300 | 0.72 | CRBN (0.51) | CRBNDDB1ARKDM4EALDH1A1 | |
| SCHEMBL31195523 | 0.72 | CRBN (0.69) | CRBNDDB1ALDH1A1 | |
| SCHEMBL1530324 | 0.71 | CRBN (0.50) | CRBNDDB1PDE3BPDE3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024037527-A1 | BTK DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-02-22 | — | — | WO | disclosed |