Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 10/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | FECH | P22830 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.39 |
| ▸ | MYLK3 | Q32MK0 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641696 | 0.90 | HTR3E (0.43) | DDB1CRBNMTORRIOK2 | |
| SCHEMBL31437046 | 0.84 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL30726420 | 0.81 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL27039529 | 0.81 | DDB1 (0.49) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL30969032 | 0.80 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL31444019 | 0.80 | CRBN (0.45) | DDB1CRBN | |
| SCHEMBL23551624 | 0.80 | PDE3B (0.41) | DDB1CRBNNOTUM | |
| Hydrochloric Acid SCHEMBL23538912 | 0.79 | PDE3B (0.41) | DDB1CRBNNOTUM | |
| SCHEMBL31331030 | 0.79 | EPHX2 (0.45) | DDB1CRBN | |
| SCHEMBL30760933 | 0.78 | CRBN (0.51) | DDB1CRBNNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119630651-A | Bifunctional compounds containing substituted pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |