SCHEMBL307621

SCHEMBL307621

[c]1ccc(C2(c3cc[c]cc3)CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.54
ESR2 Q92731 4/20 0.54
ALDH1A1 P00352 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
LMNA P02545 2/20 0.39
ALOX12 P18054 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
ACHE P22303 1/20 0.39
PSMB1 P20618 1/20 0.37
PSMB5 P28074 1/20 0.37
PSMB2 P49721 1/20 0.37
OPRM1 P35372 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C9 P11712 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD11B1 P28845 1/20 0.31
HSD11B2 P80365 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5135078 0.91 ESR1 (0.47) ESR1ESR2ALDH1A1L3MBTL1OPRM1
SCHEMBL8058589 0.84 OPRM1 (0.48) ESR1ESR2ALDH1A1L3MBTL1OPRM1
SCHEMBL12474042 0.81 ESR2 (0.69) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL10563652 0.80 ESR1 (0.46) ESR1ESR2ALDH1A1L3MBTL1OPRM1
SCHEMBL10390748 0.79 ESR1 (0.37) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL21407078 0.78 ALDH1A1 (0.40) ESR1ESR2ALDH1A1L3MBTL1LMNA
SCHEMBL28200394 0.78 ESR1 (0.35) ESR1ESR2ALDH1A1L3MBTL1OPRM1
SCHEMBL27949116 0.76 ALDH1A1 (0.31) ESR1ESR2ALDH1A1L3MBTL1
SCHEMBL25674 0.76 ALDH1A1 (0.31) ESR1ESR2ALDH1A1L3MBTL1
SCHEMBL28164133 0.76 ALDH1A1 (0.31) ESR1ESR2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418100-A Crack-free electrophotographic imaging device and method of making same XEROX CORPORATION (US) 1995-05-23 US claimed
WO-2024128254-A1 HEAT-SENSITIVE RECORDING BODY 王子ホールディングス株式会社 2024-06-20 WO disclosed
US-11993095-B2 Heat-sensitive recording material Oji Holdings Corporation (JP) 2024-05-28 US disclosed
EP-4372026-A2 POLYMERIC BINDER AND ALL-SOLID-STATE SECONDARY BATTERY Teijin Limited (JP) 2024-05-22 EP disclosed
US-20240140124-A1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD OF MANUFACTURING THE SAME OJI HOLDING CORPORATION (JP) 2024-05-02 US disclosed
US-20240145113-A1 CONDUCTIVE COMPOSITION, CONDUCTIVE PASTE, ELECTRIC CIRCUIT, FLEXIBLE ELECTRIC CIRCUIT BODY AND METHOD OF PRODUCING MOLDED BODY NAMICS CORPORATION (JP) 2024-05-02 US disclosed
US-20230391126-A1 HEAT-SENSITIVE RECORDING BODY Oji Holdings Corporation (JP) 2023-12-07 US disclosed
WO-2023199975-A1 THERMOSENSITIVE RECORDING MEDIUM 王子ホールディングス株式会社 2023-10-19 WO disclosed
WO-2023195511-A1 HEAT-SENSITIVE RECORDING MATERIAL 王子ホールディングス株式会社 2023-10-12 WO disclosed
US-20230271444-A1 HEAT-SENSITIVE RECORDING MATERIAL Oji Holdings Corporation (JP) 2023-08-31 US disclosed
US-5236883-A Improved resistance to water, oil and plasticizers OJI PAPER CO., LTD. (JP) 1993-08-17 US disclosed
EP-0542117-A1 Process for the preparation of aryle esters of chloroformic acid BASF Aktiengesellschaft (DE) 1993-05-19 EP disclosed
EP-0542132-A1 Process for the preparation of aryle esters of chloroformic acid BASF Aktiengesellschaft (DE) 1993-05-19 EP disclosed
EP-0473448-A1 Electrophotographic imaging member XEROX CORPORATION (US) 1992-03-04 EP disclosed
EP-0431594-A1 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-06-12 EP disclosed
EP-0189760-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1989-07-19 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed
WO-1986000080-A1 POLYCARBONATES EXHIBITING IMPROVED HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1986-01-03 WO disclosed
EP-0040741-A1 Process for the preparation of chloroformic-acid aryl esters BAYER AG (DE) 1981-12-02 EP disclosed