Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KHK | P50053 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762357 | 0.88 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1HPGDKHK | |
| SCHEMBL30762523 | 0.82 | ALDH1A1 (0.49) | KMT2AMEN1NPC1RAB9APIK3CA | |
| SCHEMBL30762528 | 0.81 | KMT2A (0.55) | KMT2AMEN1NPC1RAB9ANPSR1 | |
| SCHEMBL30762629 | 0.76 | ALDH1A1 (0.45) | KMT2AMEN1PIK3CANPSR1ALDH1A1 | |
| SCHEMBL30762361 | 0.75 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HPGDKHK | |
| SCHEMBL30762651 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1NPSR1ALDH1A1HPGD | |
| SCHEMBL23110061 | 0.74 | HTT (0.70) | KMT2AMEN1NPC1RAB9APIK3CA | |
| SCHEMBL3776763 | 0.74 | SMN1; SMN2 (0.61) | KMT2AMEN1NPC1RAB9APIK3CA | |
| SCHEMBL20435733 | 0.74 | PIK3CA (0.51) | KMT2AMEN1NPC1RAB9APIK3CA | |
| SCHEMBL30762465 | 0.73 | KMT2A (0.44) | KMT2AMEN1NPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |