Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762625 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDKHKHSD17B10GAA | |
| SCHEMBL30762381 | 0.79 | KDM4E (0.43) | ALDH1A1HPGDHSD17B10GAAHTT | |
| SCHEMBL30762534 | 0.77 | PIK3CA (0.55) | — | |
| SCHEMBL30762573 | 0.77 | HTT (0.50) | HTTATML3MBTL1MAPK1KMT2A | |
| SCHEMBL30762385 | 0.75 | HTT (0.47) | ALDH1A1HPGDKHKHSD17B10GAA | |
| SCHEMBL30762659 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDKHKHSD17B10GAA | |
| SCHEMBL30762375 | 0.74 | HTT (0.49) | HTTATML3MBTL1MAPK1CYP1A2 | |
| SCHEMBL30762612 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDKHKHSD17B10GAA | |
| SCHEMBL30762461 | 0.72 | HTT (0.47) | ALDH1A1HTTTSHRATML3MBTL1 | |
| SCHEMBL30762525 | 0.69 | ATR (0.47) | ALDH1A1HPGDGAAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |