Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839404 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762856 | 0.90 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839368 | 0.90 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839119 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762949 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839443 | 0.88 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762890 | 0.88 | ALDH1A1 (0.66) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839045 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ERECQLALDH2 | |
| SCHEMBL30762911 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ERECQLALDH2 | |
| SCHEMBL20839106 | 0.86 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | claimed |
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | disclosed |