Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.54 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839368 | 1.00 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762850 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839404 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839119 | 0.90 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762949 | 0.90 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839098 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762942 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839106 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL20839471 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA | |
| SCHEMBL30762868 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ERECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | claimed |
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | disclosed |