SCHEMBL4416620

SCHEMBL4416620

Cc1cccc(NC(=O)Nc2cccc(C)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.77
KMT2A Q03164 4/20 0.77
PKM P14618 1/20 0.77
SAE1 Q9UBE0 1/20 0.74
UBA2 Q9UBT2 1/20 0.74
HSD17B10 Q99714 1/20 0.74
NPC1 O15118 5/20 0.70
RAB9A P51151 5/20 0.70
ALDH1A1 P00352 1/20 0.68
GBA1 P04062 1/20 0.68
MAPK1 P28482 1/20 0.68
MEN1 O00255 3/20 0.67
RXFP1 Q9HBX9 1/20 0.67
MAPT P10636 2/20 0.66
CASP3 P42574 1/20 0.66
SENP7 Q9BQF6 1/20 0.66
SENP6 Q9GZR1 1/20 0.66
GAA P10253 1/20 0.64
CNR1 P21554 1/20 0.63
LMNA P02545 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29703055 1.00 SMN1; SMN2 (0.77) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL259602 0.94 SMN1; SMN2 (0.75) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL31054278 0.94 SMN1; SMN2 (0.75) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL5852140 0.92 SAE1 (0.76) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL2632867 0.90 SAE1 (0.68) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL16500681 0.89 KMT2A (0.79) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL709095 0.89 DDX3X (0.79) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL22588905 0.89 SAE1 (0.71) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL29555903 0.89 RAB9A (0.69) SMN1; SMN2KMT2APKMSAE1UBA2
SCHEMBL9036479 0.88 HSD17B10 (0.65) SMN1; SMN2KMT2APKMSAE1UBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080227999-A1 Heterogeneous Supported Catalytic Carbamate Process MOLZAHN DAVID C 2008-09-18 US claimed
EP-1943214-A2 HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS Dow Gloval Technologies Inc. (US) 2008-07-16 EP claimed
WO-2007015852-A2 HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-02-08 WO claimed
JP-60255849-A None JP disclosed
CN-221621330-U Welding fixture with clamping and calibrating mechanism 金威德智能装备(江苏)有限公司 2024-08-30 CN disclosed
WO-2023176554-A1 COGNITIVE-FUNCTION-IMPROVING AGENT 国立大学法人東北大学 2023-09-21 WO disclosed
CN-219348740-U Flexible multifunctional sensing network 华东理工大学 2023-07-14 CN disclosed
CN-114605408-B 5-hydroxy-1, 3-disubstituted phenylpyrido [2,3-d ] pyrimidine compound and preparation method and application thereof 沈阳药科大学 2023-06-16 CN disclosed
WO-2023102209-A1 CLAUDIN INHIBITORS AND METHODS OF USE THEREOF THE UNIVERSITY OF CHICAGO (US) 2023-06-08 WO disclosed
CN-115684355-A Flexible multifunctional sensing network and manufacturing method thereof 华东理工大学 2023-02-03 CN disclosed
CN-114605408-A 5-hydroxy-1, 3-disubstituted phenyl pyrido [2,3-d ] pyrimidine compound and preparation method and application thereof 沈阳药科大学 2022-06-10 CN disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
US-4567287-A Preparation of carbamates from organic carbonates and aromatic ureas THE UPJOHN CO. (US) 1986-01-28 US disclosed
JP-S60255849-A POLYPHENYLENE ETHER COMPOSITION HAVING IMPROVED MOLDABILITY MITSUBISHI PETROCHEM CO LTD 1985-12-17 JP disclosed
EP-0142670-A2 A process for the preparation of known herbicidally active phenyl carbamates BEROL NOBEL (SUISSE) S.A. (CH) 1985-05-29 EP disclosed
US-4480110-A FROM SUBSTITUTED UREAS AND ALCOHOL BAYER AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed
US-4430505-A UREA, PRIMARY AMINES, ALCOHOLS BAYER AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed
US-4381404-A Process for the production of N,O-disubstituted urethanes and use thereof as starting materials for the production of organic isocyanates BAYER AKTIENGESELLSCHAFT (DE) 1983-04-26 US disclosed
US-4084056-A FROM AN AROMATIC AMIDE AND A GROUP IA OR IIA HYPOCHLORITE WITH A CARBAMATE SUBSTITUTED PHENOL AB BOFORS (SW) 1978-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227999-A1 Heterogeneous Supported Catalytic Carbamate Process CPS1, CAT, CA7 SMN1; SMN2 3171/4885KMT2A 427/4885PKM 1790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.