Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21595516 | 1.00 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL30763155 | 0.85 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21595562 | 0.85 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21595543 | 0.82 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21595502 | 0.78 | MAPT (0.64) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20302473 | 0.78 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21595501 | 0.78 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21595527 | 0.78 | ALDH1A1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30763008 | 0.78 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL30763073 | 0.78 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469714-B | 1,2, 4-triazole derivatives as tankyrase inhibitors | 奥斯陆大学国家医院 | 2024-03-01 | — | — | CN | disclosed |