Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | CCND1 | P24385 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29161608 | 1.00 | TNF (0.56) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL1035977 | 0.84 | TNF (0.56) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL4552574 | 0.84 | TNF (0.63) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL28525351 | 0.83 | TNF (0.61) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL29809443 | 0.82 | TNF (0.64) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL1757376 | 0.78 | TNF (0.53) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL1238170 | 0.78 | TNF (0.52) | TNFCDK4CCND1ACHEKDM4E | |
| SCHEMBL28525147 | 0.78 | TNF (0.59) | TNFACHEKDM4EPSMB1PSMB5 | |
| SCHEMBL13046538 | 0.78 | TNF (0.56) | TNFACHEKDM4EPSMB1PSMB5 | |
| SCHEMBL29809435 | 0.78 | TNF (0.59) | TNFACHEKDM4EPSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624160-A | Preparation method of cyclic substituted 2-pyridone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117624160-A | Preparation method of cyclic substituted 2-pyridone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | disclosed |