SCHEMBL1035977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30763526	0.84	TNF (0.56)	TNFACHECDK4CCND1KDM4E
	SCHEMBL29161608	0.84	TNF (0.56)	TNFACHECDK4CCND1KDM4E
	SCHEMBL4552574	0.84	TNF (0.63)	TNFACHECDK4CCND1KDM4E
	SCHEMBL28525351	0.83	TNF (0.61)	TNFACHECDK4CCND1KDM4E
	SCHEMBL29809443	0.82	TNF (0.64)	TNFACHECDK4CCND1KDM4E
	SCHEMBL1757376	0.78	TNF (0.53)	TNFACHECDK4CCND1KDM4E
	SCHEMBL1238170	0.78	TNF (0.52)	TNFACHECDK4CCND1KDM4E
	SCHEMBL13046538	0.78	TNF (0.56)	TNFACHEKDM4EPSMB1PSMB5
	SCHEMBL28525147	0.78	TNF (0.59)	TNFACHEKDM4EPSMB1PSMB5
	SCHEMBL29809435	0.78	TNF (0.59)	TNFACHEKDM4EPSMB1PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.