SCHEMBL30764103

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27203396	0.82	TSHR (0.45)	HCAR2TSHRALDH1A1GAATP53
	SCHEMBL21891715	0.82	TSHR (0.45)	HCAR2TSHRALDH1A1GAATP53
	SCHEMBL30764091	0.82	HCAR2 (0.36)	HCAR2TSHRALDH1A1GAATP53
	SCHEMBL5207475	0.76	CHRNB2 (0.32)	CHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL5208815	0.74	CHRNB2 (0.31)	CHRNB2CHRNB4CHRNA3CHRNA4
	SCHEMBL429457	0.74	TSHR (0.42)	TSHRALDH1A1ZDHHC20CHRNB2CHRNB4
	SCHEMBL4721437	0.72	FFAR3 (0.33)	TSHRTP53
	Fumaric Acid SCHEMBL11114498	0.72	TSHR (0.56)	HCAR2TSHRALDH1A1GAATP53
	Fumaric Acid SCHEMBL28661687	0.72	TSHR (0.50)	HCAR2TSHRALDH1A1GAATP53
	SCHEMBL10824794	0.71	CHRNB2 (0.38)	ALDH1A1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.