Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617070 | 1.00 | XPO1 (0.42) | XPO1PIM1PIM2LCKSYK | |
| SCHEMBL21621090 | 0.91 | SCN9A (0.42) | XPO1PIM1PIM2SYKACP1 | |
| SCHEMBL21617025 | 0.85 | XPO1 (0.43) | XPO1PIM1PIM2MAPK11MAPK14 | |
| SCHEMBL30764836 | 0.85 | XPO1 (0.43) | XPO1PIM1PIM2MAPK11MAPK14 | |
| SCHEMBL21617048 | 0.84 | XPO1 (0.42) | XPO1PIM1PIM2LCKKDM4E | |
| SCHEMBL30764811 | 0.84 | XPO1 (0.42) | XPO1PIM1PIM2LCKKDM4E | |
| SCHEMBL21617023 | 0.83 | XPO1 (0.43) | XPO1PIM1PIM2SYKTDP1 | |
| Trifluoroacetic Acid SCHEMBL21617076 | 0.82 | RAF1 (0.44) | XPO1SYKNR1H2NR1H3GRM5 | |
| SCHEMBL21621091 | 0.82 | KDR (0.41) | XPO1SYKTDP1MEN1KMT2A | |
| SCHEMBL30764789 | 0.82 | KDR (0.41) | XPO1SYKTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566899-B | phenyl-N-quinoline derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2024-01-30 | — | — | CN | disclosed |