Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | XPO1 | O14980 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621091 | 1.00 | KDR (0.41) | KDRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL21617050 | 0.89 | SCN9A (0.50) | KDRMEN1KMT2AMAPTXPO1 | |
| SCHEMBL30603856 | 0.85 | MEN1 (0.60) | KDRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29110571 | 0.85 | MEN1 (0.60) | KDRMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL18434270 | 0.84 | RAB9A (0.55) | MEN1KMT2AMAPTMAPK1XPO1 | |
| SCHEMBL1702145 | 0.82 | CTSC (0.51) | SYKDHFRCTSC | |
| SCHEMBL21621090 | 0.82 | SCN9A (0.42) | XPO1ALDH1A1SYKSCN9AKDM4E | |
| SCHEMBL21617070 | 0.82 | XPO1 (0.42) | MEN1KMT2AXPO1ALDH1A1SYK | |
| SCHEMBL30764783 | 0.82 | XPO1 (0.42) | MEN1KMT2AXPO1ALDH1A1SYK | |
| SCHEMBL21617073 | 0.82 | SCN9A (0.48) | MEN1KMT2AMAPTMAPK1XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566899-B | phenyl-N-quinoline derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2024-01-30 | — | — | CN | disclosed |