SCHEMBL30764801

SCHEMBL30764801

Cc1cc(Oc2ccccc2F)ccc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCK P35557 3/20 0.48
PARP10 Q53GL7 1/20 0.47
ALDH1A1 P00352 4/20 0.46
GAA P10253 2/20 0.46
RCE1 Q9Y256 1/20 0.45
HTR2A P28223 3/20 0.41
SLC6A4 P31645 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ESR1 P03372 1/20 0.41
KCNH2 Q12809 1/20 0.38
NR4A1 P22736 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16792505 1.00 GCK (0.48) GCKPARP10ALDH1A1GAARCE1
SCHEMBL16792417 0.87 GAA (0.44) GCKALDH1A1GAARCE1HTR2A
SCHEMBL4060551 0.87 PARP10 (0.47) GCKPARP10ALDH1A1GAARCE1
SCHEMBL20084804 0.84 HTR2A (0.55) GCKPARP10ALDH1A1GAAHTR2A
SCHEMBL18331917 0.84 PARP10 (0.51) GCKPARP10ALDH1A1GAARCE1
SCHEMBL21083457 0.83 PARP10 (0.47) GCKPARP10ALDH1A1GAARCE1
SCHEMBL16792540 0.80 PARP10 (0.47) GCKPARP10ALDH1A1GAARCE1
SCHEMBL18332182 0.80 ALDH1A1 (0.44) GCKPARP10ALDH1A1GAAHTR2A
SCHEMBL16792734 0.80 PARP10 (0.44) GCKPARP10ALDH1A1GAAHTR2A
SCHEMBL1374851 0.79 NR4A1 (0.48) GCKALDH1A1GAAHTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566899-B phenyl-N-quinoline derivatives for the treatment of RNA viral infections ABIVAX公司 2024-01-30 CN disclosed