Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264005 | 0.88 | HSD17B10 (0.52) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL18264008 | 0.84 | HSD17B10 (0.49) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL18264010 | 0.82 | HSD17B10 (0.47) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL1850349 | 0.82 | TSHR (0.47) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL1856598 | 0.78 | TSHR (0.44) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL22866726 | 0.77 | TSHR (0.48) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL29561227 | 0.77 | TSHR (0.48) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL1851435 | 0.77 | HSD17B10 (0.48) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL18264000 | 0.75 | HDAC4 (0.55) | JAK2JAK1TYK2JAK3TSHR | |
| SCHEMBL18263990 | 0.74 | ALDH1A1 (0.45) | JAK2JAK1TYK2JAK3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |