Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765367 | 0.91 | CCNT1 (0.40) | KCNH2MTORHPGDRIPK1HDAC4 | |
| SCHEMBL32672591 | 0.87 | PIK3C3 (0.34) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL32672625 | 0.86 | NPC1 (0.42) | HPGDALDH1A1 | |
| SCHEMBL27267083 | 0.86 | NPC1 (0.42) | HPGDALDH1A1 | |
| SCHEMBL27262760 | 0.86 | NPC1 (0.42) | HPGDALDH1A1 | |
| SCHEMBL32672657 | 0.86 | NPC1 (0.42) | HPGDALDH1A1 | |
| SCHEMBL32672563 | 0.86 | NPC1 (0.42) | HPGDALDH1A1 | |
| SCHEMBL32672561 | 0.86 | GLRA1 (0.38) | — | |
| SCHEMBL32672619 | 0.86 | GLRA1 (0.38) | — | |
| SCHEMBL32672602 | 0.84 | TGFBR1 (0.35) | TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042772-A1 | FURO PYRIMIDINE DERIVATES | MERCK PATENT GMBH (DE) | 2026-02-12 | — | — | US | disclosed |
| EP-4568970-A1 | FURO PYRIMIDINE DERIVATES | Merck Patent GmbH (DE) | 2025-06-18 | — | — | EP | disclosed |
| CN-119948032-A | Furanopyrimidine derivatives | 默克专利股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024033281-A1 | FURO PYRIMIDINE DERIVATES | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042772-A1 | FURO PYRIMIDINE DERIVATES | HAVCR2, CYC1, CNKSR1 | TNKS 886/4885KCNH2 3589/4885PIK3CD 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.