Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 11/20 | 0.34 |
| ▸ | RARB | P10826 | 11/20 | 0.34 |
| ▸ | RARG | P13631 | 11/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27267047 | 0.92 | CTSB (0.32) | — | |
| SCHEMBL27262769 | 0.89 | KEAP1 (0.39) | RXRARXRBKDM4ETDP1 | |
| SCHEMBL32672588 | 0.89 | CLK4 (0.40) | KDM4E | |
| SCHEMBL32672585 | 0.89 | KEAP1 (0.39) | RXRARXRBKDM4ETDP1 | |
| SCHEMBL32672551 | 0.88 | CA12 (0.36) | — | |
| SCHEMBL27262763 | 0.88 | CA12 (0.36) | — | |
| SCHEMBL32672573 | 0.85 | PTGS2 (0.33) | — | |
| SCHEMBL27263639 | 0.85 | PTGS2 (0.33) | — | |
| SCHEMBL27262359 | 0.85 | RARA (0.35) | TGFBR1RARARARBRARGTNKS | |
| SCHEMBL30765173 | 0.84 | TNKS (0.43) | TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042772-A1 | FURO PYRIMIDINE DERIVATES | MERCK PATENT GMBH (DE) | 2026-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042772-A1 | FURO PYRIMIDINE DERIVATES | HAVCR2, CYC1, CNKSR1 | TGFBR1 476/4885RARA 1447/4885RARB 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.