Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765107 | 0.86 | HSD11B1 (0.46) | MAOBIDO1NPC1RAB9AMAPT | |
| SCHEMBL2285971 | 0.82 | MAOB (0.57) | MAOBHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23235823 | 0.81 | MCL1 (0.49) | MAOBIDO1MCL1HTR1ASLC6A2 | |
| SCHEMBL993614 | 0.80 | MAOB (0.61) | MAOBIDO1MCL1PARP15PARP10 | |
| SCHEMBL19745238 | 0.74 | MAOB (0.51) | MAOBPARP15PARP10PARP14KCNH2 | |
| SCHEMBL10549309 | 0.73 | MCL1 (0.38) | MAOBIDO1MCL1SLC6A2SLC6A4 | |
| SCHEMBL30331042 | 0.72 | MCL1 (0.56) | MAOBIDO1MCL1HTR1ASLC6A2 | |
| SCHEMBL5018947 | 0.72 | TRPV4 (0.38) | LMNAKCNH2KDM4EGAA | |
| SCHEMBL17644774 | 0.71 | MAOB (0.68) | MAOBIDO1MCL1PARP15PARP10 | |
| SCHEMBL1154287 | 0.71 | MCL1 (0.55) | MAOBIDO1MCL1HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |