Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722404 | 0.84 | PDE4C (0.46) | GAAUSP2KDM4EHPGDHSD17B10 | |
| SCHEMBL27260526 | 0.84 | PDE4C (0.43) | ALDH1A1GAAUSP2CYP1A2KDM4E | |
| SCHEMBL30765218 | 0.84 | PDE4C (0.43) | ALDH1A1GAAUSP2CYP1A2KDM4E | |
| SCHEMBL722179 | 0.84 | CA1 (0.58) | GAAUSP2KDM4EHPGDHSD17B10 | |
| SCHEMBL722188 | 0.82 | PDE4C (0.44) | KMT2AALDH1A1GAAUSP2KDM4E | |
| SCHEMBL723230 | 0.81 | JAK1 (0.54) | SMN1; SMN2KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL30765331 | 0.81 | JAK1 (0.54) | SMN1; SMN2KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL30765266 | 0.81 | PIK3CD (0.45) | KMT2AALDH1A1BRD4GAAUSP2 | |
| SCHEMBL30765417 | 0.80 | BRD4 (0.46) | SMN1; SMN2ALDH1A1BRD4KDM4ELMNA | |
| SCHEMBL27260528 | 0.80 | PDE4C (0.42) | ALDH1A1GAAUSP2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |