Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.64 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558511 | 0.87 | AKR1C3 (0.60) | AKR1C3AKR1C2MAPK1LMNAHTT | |
| SCHEMBL26657585 | 0.85 | PTGS2 (0.67) | AKR1C3AKR1C2DHODHRXRAPTGS2 | |
| SCHEMBL29793330 | 0.85 | PTGS2 (0.67) | AKR1C3AKR1C2DHODHRXRAPTGS2 | |
| SCHEMBL22189997 | 0.84 | AKR1C3 (0.56) | AKR1C3AKR1C2CYP2C8MAPK1LMNA | |
| SCHEMBL26911126 | 0.84 | CYP2C19 (0.62) | AKR1C3AKR1C2CYP2C8MAPK1LMNA | |
| SCHEMBL23484836 | 0.82 | CYP2C19 (0.60) | AKR1C3AKR1C2CYP2C8MAPK1LMNA | |
| SCHEMBL2744367 | 0.81 | MAPT (0.54) | CYP2C8LMNARAB9AKDM4ERXRA | |
| SCHEMBL29651459 | 0.81 | LMNA (0.62) | CYP2C8MAPK1LMNAHTTRAB9A | |
| SCHEMBL1607173 | 0.81 | LMNA (0.62) | CYP2C8MAPK1LMNAHTTRAB9A | |
| SCHEMBL29788306 | 0.81 | CYP2C19 (0.58) | AKR1C3AKR1C2CYP2C8MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |