Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558534 | 0.93 | KDM4C (0.48) | KDM4CMAPTTAS1R3TAS1R1CYP1A2 | |
| SCHEMBL30765526 | 0.89 | KDM4C (0.46) | KDM4CMAPTTAS1R3TAS1R1CYP1A2 | |
| SCHEMBL30765668 | 0.88 | GAA (0.50) | KDM4CMAPTTAS1R3TAS1R1CYP1A2 | |
| SCHEMBL30765992 | 0.84 | MAPT (0.52) | KDM4CMAPTTAS1R3TAS1R1CYP1A2 | |
| SCHEMBL30765849 | 0.81 | KDM4C (0.46) | KDM4CMAPTTAS1R3TAS1R1CYP1A2 | |
| SCHEMBL30765706 | 0.80 | ELANE (0.47) | EGLN1ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL30765910 | 0.79 | PDE4B (0.48) | KDM4CMAPTEGLN1TSHRALDH1A1 | |
| SCHEMBL30765610 | 0.77 | MAPT (0.52) | KDM4CMAPTTAS1R3TAS1R1CYP1A2 | |
| SCHEMBL6801188 | 0.76 | SMN1; SMN2 (0.48) | MAPTTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL6799310 | 0.75 | RAB9A (0.54) | ALDH1A1LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |