Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765501 | 0.92 | ELANE (0.44) | ELANEALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL30766097 | 0.90 | ASPH (0.49) | ELANEKDM4EHPGDEGLN1 | |
| SCHEMBL30766150 | 0.89 | GAA (0.52) | ELANEALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL23461187 | 0.83 | KDM4E (0.47) | ELANEKDM4E | |
| SCHEMBL30766006 | 0.82 | KDM4E (0.42) | ELANEKDM4EEGLN1 | |
| SCHEMBL30765807 | 0.82 | CASP1 (0.47) | ELANELMNA | |
| SCHEMBL30766118 | 0.82 | ELANE (0.41) | ELANEKDM4E | |
| SCHEMBL30765659 | 0.81 | ELANE (0.39) | ELANEKDM4ENPC1RAB9AEGLN1 | |
| SCHEMBL30765994 | 0.81 | ELANE (0.46) | ELANEALDH1A1KDM4EEGLN1 | |
| SCHEMBL6799310 | 0.80 | RAB9A (0.54) | ELANEALDH1A1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |