Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 9/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765638 | 0.93 | GAA (0.41) | GAAL3MBTL1ELANEBCHEADORA3 | |
| SCHEMBL30765687 | 0.90 | BCHE (0.41) | ELANEBCHEADORA3ADORA2BNPC1 | |
| SCHEMBL30765978 | 0.84 | ELANE (0.41) | ELANEBCHEADORA3ADORA2BNPC1 | |
| SCHEMBL30765463 | 0.84 | GAA (0.44) | GAAL3MBTL1ELANEADORA3ADORA2B | |
| SCHEMBL30765476 | 0.83 | ELANE (0.40) | ELANEBCHEAVPR1BNPC1RAB9A | |
| SCHEMBL30765613 | 0.83 | GAA (0.50) | GAAL3MBTL1ELANEMEN1KMT2A | |
| SCHEMBL30765744 | 0.83 | BCHE (0.38) | GAAL3MBTL1BCHEMEN1KMT2A | |
| SCHEMBL30766052 | 0.82 | KLK7 (0.42) | ELANEBCHE | |
| SCHEMBL30766150 | 0.81 | GAA (0.52) | GAAL3MBTL1ELANEAVPR1BMEN1 | |
| SCHEMBL30765630 | 0.80 | GAA (0.47) | GAAL3MBTL1ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |