Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765687 | 0.92 | BCHE (0.41) | ELANECASP1BCHENPC1RAB9A | |
| SCHEMBL30765476 | 0.91 | ELANE (0.40) | ELANECASP1BCHENPC1RAB9A | |
| SCHEMBL30765503 | 0.87 | BCHE (0.41) | BCHEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765659 | 0.86 | ELANE (0.39) | ELANECASP1NPC1RAB9AKDM4E | |
| SCHEMBL30765608 | 0.84 | GAA (0.41) | ELANEBCHENPC1RAB9AADORA3 | |
| SCHEMBL30766052 | 0.84 | KLK7 (0.42) | ELANEBCHE | |
| SCHEMBL30765638 | 0.84 | GAA (0.41) | ELANEBCHEADORA3ADORA2B | |
| SCHEMBL30765555 | 0.83 | CASP1 (0.42) | ELANECASP1 | |
| SCHEMBL30765905 | 0.82 | ELANE (0.39) | ELANECASP1NPC1RAB9AKDM4E | |
| SCHEMBL31558528 | 0.81 | BCHE (0.40) | BCHEKDM4EASPHRIOX2KDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |