SCHEMBL30765638

SCHEMBL30765638

CCCCOC(=O)Cn1c(-c2ccc(O[C@@H]3CO[C@H]4[C@@H]3OC[C@H]4OCc3ccccc3)cc2)ncc(NCCCc2ccccc2)c1=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ELANE P08246 12/20 0.40
BCHE P06276 3/20 0.37
KLK7 P49862 3/20 0.36
KLK5 Q9Y337 3/20 0.36
ADORA3 P0DMS8 1/20 0.35
ADORA2B P29275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765608 0.93 GAA (0.41) GAAL3MBTL1ELANEBCHEADORA3
SCHEMBL30766052 0.90 KLK7 (0.42) ELANEBCHEKLK7KLK5
SCHEMBL30765613 0.84 GAA (0.50) GAAL3MBTL1ELANE
SCHEMBL30765978 0.84 ELANE (0.41) ELANEBCHEADORA3ADORA2B
SCHEMBL30765463 0.83 GAA (0.44) GAAL3MBTL1ELANEADORA3ADORA2B
SCHEMBL30765476 0.83 ELANE (0.40) ELANEBCHEKLK7KLK5
SCHEMBL30765664 0.83 BCHE (0.44) ELANEBCHEKLK7KLK5
SCHEMBL30765744 0.82 BCHE (0.38) GAAL3MBTL1BCHE
SCHEMBL30765687 0.82 BCHE (0.41) ELANEBCHEADORA3ADORA2B
SCHEMBL30766150 0.80 GAA (0.52) GAAL3MBTL1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 WO disclosed