Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558527 | 0.67 | AKT1 (0.36) | LMNAALDH1A1TSHRNPSR1MAPK1 | |
| SCHEMBL31558437 | 0.65 | AKT1 (0.35) | ALDH1A1TSHRSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL31558496 | 0.61 | IDH1 (0.37) | ALDH1A1NPSR1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL31558557 | 0.61 | POLB (0.37) | LMNAALDH1A1NPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL6649823 | 0.58 | MEN1 (0.44) | LMNAALDH1A1TSHRNPSR1MAPK1 | |
| SCHEMBL31558470 | 0.56 | LMNA (0.37) | LMNAALDH1A1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL20356854 | 0.55 | MEN1 (0.52) | LMNAALDH1A1TSHRNPSR1MAPK1 | |
| SCHEMBL521967 | 0.55 | ALDH1A1 (0.83) | LMNAALDH1A1NPSR1L3MBTL1KMT2A | |
| SCHEMBL11464739 | 0.55 | GRIA4 (0.42) | ALDH1A1TSHRNPSR1L3MBTL1KMT2A | |
| SCHEMBL31558502 | 0.54 | NOTUM (0.34) | LMNAALDH1A1MAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |