Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765510 | 0.88 | L3MBTL1 (0.41) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765675 | 0.86 | L3MBTL1 (0.40) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765767 | 0.86 | GAA (0.40) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30766030 | 0.86 | L3MBTL1 (0.40) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765977 | 0.86 | GAA (0.51) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765742 | 0.86 | GAA (0.39) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765471 | 0.86 | GAA (0.39) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765969 | 0.84 | GAA (0.42) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30766034 | 0.84 | GAA (0.38) | GAAL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL30765801 | 0.82 | LMNA (0.41) | GAAL3MBTL1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |