Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558470 | 0.89 | LMNA (0.37) | ALDH1A1HPGDKDM4ELMNATP53 | |
| SCHEMBL30765981 | 0.89 | LMNA (0.37) | ALDH1A1HPGDKDM4ELMNATP53 | |
| SCHEMBL30765722 | 0.88 | ELANE (0.35) | ALDH1A1HPGDKDM4ELMNAELANE | |
| SCHEMBL30765879 | 0.87 | GAA (0.41) | ALDH1A1HPGDLMNATP53ALOX15 | |
| SCHEMBL30765975 | 0.87 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4ELMNAELANE | |
| SCHEMBL31558585 | 0.87 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4ELMNAELANE | |
| SCHEMBL30765563 | 0.85 | PDE2A (0.40) | ALDH1A1KDM4EELANE | |
| SCHEMBL30765944 | 0.84 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4ELMNATP53 | |
| SCHEMBL30765991 | 0.84 | ELANE (0.42) | ALDH1A1KDM4ELMNAELANEJAK2 | |
| SCHEMBL30766151 | 0.84 | ELANE (0.37) | ALDH1A1HPGDLMNATP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |