Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765582 | 0.87 | KDM4C (0.42) | MAPTKDM4CMTNR1BALDH1A1KDM4E | |
| SCHEMBL30765865 | 0.85 | NTRK1 (0.37) | KDM4CMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30765874 | 0.82 | NTRK1 (0.41) | MTNR1BALDH1A1KDM4E | |
| SCHEMBL30765852 | 0.79 | NTRK1 (0.38) | MEN1KMT2A | |
| SCHEMBL30765910 | 0.78 | PDE4B (0.48) | ATMPDE4BMAPTKDM4CMEN1 | |
| SCHEMBL30765520 | 0.76 | NTRK1 (0.41) | MAPTMTNR1BALDH1A1KDM4E | |
| SCHEMBL30765999 | 0.73 | PDE4B (0.44) | ATMPDE4BMAPTKDM4CMEN1 | |
| SCHEMBL30765718 | 0.71 | NTRK1 (0.45) | MTNR1BMEN1KMT2A | |
| SCHEMBL30765849 | 0.69 | KDM4C (0.46) | MAPTKDM4CALDH1A1KDM4EPOLB | |
| SCHEMBL30765506 | 0.68 | NTRK1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |