Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 8/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765520 | 0.87 | NTRK1 (0.41) | NTRK1NAMPTNTRK3F2PRSS1 | |
| SCHEMBL30765718 | 0.86 | NTRK1 (0.45) | NTRK1NTRK3F2PRSS1MTNR1B | |
| SCHEMBL30765865 | 0.86 | NTRK1 (0.37) | NTRK1NAMPTF2PRSS1IDE | |
| SCHEMBL30765506 | 0.84 | NTRK1 (0.51) | NTRK1NTRK3 | |
| SCHEMBL30765852 | 0.84 | NTRK1 (0.38) | NTRK1NAMPTNTRK3F2 | |
| SCHEMBL30765715 | 0.82 | ATM (0.40) | MTNR1BALDH1A1KDM4E | |
| SCHEMBL30765816 | 0.77 | NTRK1 (0.38) | NTRK1NAMPTNTRK3 | |
| SCHEMBL30765486 | 0.74 | NTRK1 (0.33) | NTRK1ALDH1A1L3MBTL1 | |
| SCHEMBL31558522 | 0.72 | MTNR1B (0.45) | NTRK1NAMPTMTNR1BIDEPIK3C3 | |
| SCHEMBL32680681 | 0.70 | ALDH1A1 (0.50) | NTRK1NAMPTMTNR1BIDEPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |