Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 3/20 | 0.38 |
| ▸ | CTRC | Q99895 | 3/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765506 | 0.91 | NTRK1 (0.51) | NTRK1NTRK3CMA1CTRC | |
| SCHEMBL30765874 | 0.86 | NTRK1 (0.41) | NTRK1F2PRSS1NTRK3MTNR1B | |
| SCHEMBL30765520 | 0.79 | NTRK1 (0.41) | NTRK1F2PRSS1NTRK3MTNR1B | |
| SCHEMBL31558522 | 0.78 | MTNR1B (0.45) | NTRK1MTNR1BIDEPPARGPPARA | |
| SCHEMBL32680681 | 0.74 | ALDH1A1 (0.50) | NTRK1MTNR1BIDEKMT2APPARG | |
| SCHEMBL31750757 | 0.74 | PPARG (0.42) | NTRK1MTNR1BIDEPPARGPPARA | |
| SCHEMBL30765582 | 0.74 | KDM4C (0.42) | NTRK1NTRK3MTNR1B | |
| SCHEMBL30765810 | 0.73 | CTRC (0.47) | NTRK1NTRK3CMA1CTRC | |
| SCHEMBL30765640 | 0.71 | NTRK1 (0.45) | NTRK1NTRK3CMA1CTRC | |
| SCHEMBL30765549 | 0.71 | PPARG (0.44) | IDEKMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |