Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765546 | 0.94 | CASP1 (0.40) | CASP1WNT3ACYP3A4HDAC3HDAC4 | |
| SCHEMBL30765555 | 0.93 | CASP1 (0.42) | CASP1WNT3ACYP3A4HDAC3HDAC4 | |
| SCHEMBL30765831 | 0.88 | CASP1 (0.40) | CASP1WNT3ACYP3A4HDAC3HDAC4 | |
| SCHEMBL30765813 | 0.85 | ELANE (0.42) | CASP1WNT3ACYP3A4BCHEELANE | |
| SCHEMBL30765694 | 0.84 | CASP1 (0.38) | CASP1WNT3ACYP3A4HDAC3HDAC4 | |
| SCHEMBL30765765 | 0.83 | CASP1 (0.43) | CASP1WNT3AKCNH2ELANE | |
| SCHEMBL30765687 | 0.83 | BCHE (0.41) | CASP1BCHEELANEPRKAG1PRKAA1 | |
| SCHEMBL30765956 | 0.78 | CASP1 (0.41) | CASP1WNT3AKCNH2ELANE | |
| SCHEMBL30765857 | 0.76 | BCHE (0.41) | CASP1BCHEELANEPRKAG1PRKAA1 | |
| SCHEMBL30765978 | 0.75 | ELANE (0.41) | CASP1BCHEELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |