Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 13/20 | 0.49 |
| ▸ | F3 | P13726 | 13/20 | 0.49 |
| ▸ | F2 | P00734 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23460740 | 0.80 | F7 (0.58) | F7F3F2PRSS1 | |
| SCHEMBL5846880 | 0.79 | F7 (0.61) | F7F3F2PRSS1 | |
| SCHEMBL14537324 | 0.78 | F2 (0.50) | F7F3F2KDM4EALDH1A1 | |
| SCHEMBL7912621 | 0.78 | TPSAB1 (0.61) | F7F3F2KDM4EALDH1A1 | |
| SCHEMBL5847197 | 0.75 | CYP1A2 (0.48) | F7F3F2ALDH1A1HPGD | |
| SCHEMBL30765610 | 0.75 | MAPT (0.52) | KDM4EALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL23461161 | 0.74 | F7 (0.47) | F7F3F2PRSS1 | |
| SCHEMBL30765992 | 0.72 | MAPT (0.52) | KDM4EALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL5845992 | 0.72 | F7 (0.62) | F7F3F2PRSS1 | |
| SCHEMBL5164865 | 0.69 | ALDH1A1 (0.45) | KDM4EALDH1A1NPSR1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |