Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.52 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.52 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.52 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829335 | 0.88 | ALOX5 (0.61) | ALOX5SMN1; SMN2ALDH1A1 | |
| SCHEMBL13792415 | 0.85 | ALOX5 (0.77) | ALOX5PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1667586 | 0.84 | ALOX5 (0.69) | ALOX5SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6465764 | 0.81 | ALOX5 (0.52) | ALOX5SMN1; SMN2 | |
| SCHEMBL5321740 | 0.80 | ALOX5 (0.55) | ALOX5PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27615885 | 0.79 | FFAR1 (0.80) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1727025 | 0.79 | KMT2A (0.62) | ALOX5FFAR1ALDH1A1 | |
| SCHEMBL3868251 | 0.78 | HSD17B10 (0.59) | ALOX5 | |
| SCHEMBL8358797 | 0.78 | CYP2D6 (0.58) | FFAR1PPARGALDH1A1 | |
| SCHEMBL27472366 | 0.77 | ALOX5 (0.61) | ALOX5FFAR1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |