Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880810 | 0.93 | CYP2D6 (0.60) | CYP2D6LTB4RLTB4R2CYP4F2CYP4A11 | |
| SCHEMBL829335 | 0.83 | ALOX5 (0.61) | ALDH1A1 | |
| SCHEMBL19932501 | 0.82 | CYP4F2 (0.61) | CYP2D6LTB4RLTB4R2CYP4F2CYP4A11 | |
| SCHEMBL5763262 | 0.82 | FFAR1 (0.70) | CYP4F2CYP4A11FFAR1MAOBMGLL | |
| SCHEMBL23771271 | 0.81 | CYP2D6 (0.71) | CYP2D6LTB4RLTB4R2CYP4F2CYP4A11 | |
| SCHEMBL1171782 | 0.80 | ALOX5 (0.54) | LTB4RLTB4R2MAOBKDM4EALDH1A1 | |
| SCHEMBL7998675 | 0.80 | FFAR1 (0.65) | LTB4RLTB4R2FFAR1MAOB | |
| SCHEMBL1667586 | 0.79 | ALOX5 (0.69) | — | |
| SCHEMBL30765759 | 0.78 | ALOX5 (0.57) | FFAR1ALDH1A1PPARG | |
| SCHEMBL8350924 | 0.78 | CYP4F2 (0.60) | CYP2D6LTB4RLTB4R2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |