Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750690 | 0.80 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19GAAL3MBTL1 | |
| SCHEMBL31751390 | 0.76 | CYP1A2 (0.69) | CYP1A2CYP2C9CYP2C19GAAL3MBTL1 | |
| SCHEMBL30766069 | 0.75 | KDM4E (0.46) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL4138763 | 0.74 | CASR (0.63) | GAAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10386808 | 0.72 | CYP1A2 (0.70) | CYP1A2CYP2C9CYP2C19GAAL3MBTL1 | |
| SCHEMBL29951529 | 0.72 | CYP1A2 (0.57) | CYP1A2CYP2C9CYP2C19GAAL3MBTL1 | |
| SCHEMBL1987381 | 0.72 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL7296961 | 0.71 | MEN1 (0.66) | CYP1A2CYP2C9CYP2C19GAAL3MBTL1 | |
| SCHEMBL30765447 | 0.71 | L3MBTL1 (0.65) | CYP1A2CYP2C9CYP2C19GAAL3MBTL1 | |
| SCHEMBL28287010 | 0.70 | KDM4E (0.78) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |