Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160756 | 0.76 | ALDH1A1 (0.51) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL11098803 | 0.73 | IDO1 (0.43) | CYP1A2CYP2C9CYP2C19TSHRMEN1 | |
| SCHEMBL1422956 | 0.73 | HPGD (0.45) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11163138 | 0.73 | SLC2A2 (0.49) | CYP1A2CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL11097622 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL30765772 | 0.72 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19TSHRMEN1 | |
| SCHEMBL1922378 | 0.71 | ADORA2B (0.42) | ALDH1A1KDM4EHPGDGAAL3MBTL1 | |
| SCHEMBL6202033 | 0.71 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL10386808 | 0.71 | CYP1A2 (0.70) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL11163273 | 0.71 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |