Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765939 | 0.92 | LMNA (0.35) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL30765836 | 0.88 | KDM4E (0.36) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL30765535 | 0.82 | F2 (0.34) | ALDH1A1MAPTKMT2AHDAC6 | |
| SCHEMBL30765838 | 0.82 | CASP1 (0.41) | LMNAHPGDKDM4EHTTHSD17B10 | |
| SCHEMBL30765580 | 0.81 | ELANE (0.39) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL30765947 | 0.80 | LMNA (0.40) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL30765465 | 0.77 | LMNA (0.39) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL30765805 | 0.76 | LMNA (0.39) | LMNAHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL30765916 | 0.75 | CMA1 (0.41) | LMNA | |
| SCHEMBL31558430 | 0.75 | HDAC6 (0.47) | LMNAHPGDKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |