Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765915 | 0.84 | SMN1; SMN2 (0.39) | NAMPTAKT1TRPV1F2CCNK | |
| SCHEMBL30765852 | 0.83 | NTRK1 (0.38) | NAMPTSRPK1TRPV1DGAT1NTRK1 | |
| SCHEMBL30765657 | 0.82 | F2 (0.36) | NAMPTAKT1TRPV1NTRK1F3 | |
| SCHEMBL30765553 | 0.81 | MAPK1 (0.37) | NAMPTAKT1NTRK1F3F2 | |
| SCHEMBL31751198 | 0.79 | MAPK1 (0.36) | NAMPTNTRK1F2CCNKCDK12 | |
| SCHEMBL30766050 | 0.77 | ELANE (0.41) | SRPK1NTRK1F3F2 | |
| SCHEMBL30765627 | 0.77 | DGAT2 (0.39) | NTRK1HDAC1F3F2MAPK1 | |
| SCHEMBL30765851 | 0.76 | NTRK1 (0.40) | NAMPTNTRK1HDAC1F3 | |
| SCHEMBL30765732 | 0.76 | NTRK1 (0.40) | SRPK1DGAT1NTRK1HDAC1F3 | |
| SCHEMBL30765840 | 0.76 | NAMPT (0.38) | NAMPTAKT1DGAT1NTRK1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |