Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765781 | 0.86 | F2 (0.33) | F2NAMPTMAPK1F3TRPV1 | |
| SCHEMBL30765880 | 0.84 | F3 (0.36) | F2NTRK1NTRK3F3 | |
| SCHEMBL30765553 | 0.84 | MAPK1 (0.37) | F2NAMPTNTRK1MAPK1AKT1 | |
| SCHEMBL30765435 | 0.83 | F2 (0.36) | F2NAMPTNTRK1MAPK1AKT1 | |
| SCHEMBL30765552 | 0.83 | LMNA (0.38) | L3MBTL1MAPK1LMNAPIK3CDPIK3CB | |
| SCHEMBL30765780 | 0.82 | NAMPT (0.40) | F2NAMPTNTRK1MAPK1CCNK | |
| SCHEMBL30766040 | 0.80 | F2 (0.36) | F2NAMPTNTRK1MAPK1NTRK3 | |
| SCHEMBL30765915 | 0.79 | SMN1; SMN2 (0.39) | F2NAMPTCCNKCDK12AKT1 | |
| SCHEMBL30766047 | 0.78 | ALDH1A1 (0.35) | L3MBTL1MAPK1TP53LMNAPIK3CD | |
| SCHEMBL30765509 | 0.78 | LMNA (0.43) | L3MBTL1MAPK1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |