SCHEMBL30765832

SCHEMBL30765832

N#CC(NCC(=O)OCc1ccccc1)c1ccccc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CNR2 P34972 1/20 0.41
SGMS2 Q8NHU3 5/20 0.41
LMNA P02545 1/20 0.41
CPB1 P15086 1/20 0.39
TSHR P16473 1/20 0.39
TACR1 P25103 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ABCC3 O15438 1/20 0.38
NR1I2 O75469 1/20 0.38
ABCB11 O95342 1/20 0.38
NR3C1 P04150 1/20 0.38
RARG P13631 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6988925 0.83 ALDH1A1 (0.47) ALDH1A1MAPK1L3MBTL1SGMS2LMNA
SCHEMBL3246690 0.78 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL3235389 0.77 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1CYP1A2CYP3A4
SCHEMBL5864545 0.76 SGMS2 (0.45) ALDH1A1CNR2SGMS2LMNACYP1A2
SCHEMBL10832272 0.71 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1CYP1A2CYP3A4
SCHEMBL8688821 0.71 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1
SCHEMBL10722003 0.70 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1LMNACYP1A2
SCHEMBL29045009 0.70 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1CYP1A2CYP3A4
SCHEMBL2816306 0.70 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL10832268 0.70 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 WO disclosed