Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 6/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765794 | 0.90 | HDAC1 (0.46) | HDAC1HDAC6HDAC8CASP1ELANE | |
| SCHEMBL6240894 | 0.81 | ELANE (0.51) | HDAC1CASP1ELANEKDM4EHSD17B10 | |
| SCHEMBL30765564 | 0.80 | ELANE (0.49) | CASP1ELANESRPK1SMN1; SMN2 | |
| SCHEMBL30765732 | 0.80 | NTRK1 (0.40) | HDAC1HDAC6HDAC8CASP1ELANE | |
| SCHEMBL5728202 | 0.78 | ELANE (0.54) | HDAC1CASP1ELANEKDM4EHSD17B10 | |
| SCHEMBL30766127 | 0.77 | TUBB4A (0.51) | HDAC1HDAC6HDAC8CASP1ELANE | |
| SCHEMBL6805612 | 0.77 | HDAC2 (0.46) | HDAC1CASP1ELANESMN1; SMN2 | |
| SCHEMBL6240974 | 0.77 | RAB9A (0.55) | CASP1ELANEKDM4ESMN1; SMN2 | |
| SCHEMBL6805801 | 0.75 | RAB9A (0.53) | CASP1ELANEKDM4ESMN1; SMN2 | |
| SCHEMBL30766058 | 0.75 | ELANE (0.43) | HDAC1HDAC6HDAC8CASP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |