Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 7/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | CMA1 | P23946 | 3/20 | 0.34 |
| ▸ | CTRC | Q99895 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31558547 | 0.87 | PDE2A (0.41) | F3NTRK1F2CMA1CTRC | |
| SCHEMBL30765665 | 0.87 | PDE2A (0.41) | F3NTRK1F2CMA1CTRC | |
| SCHEMBL30765781 | 0.85 | F2 (0.33) | F3F2 | |
| SCHEMBL30765657 | 0.84 | F2 (0.36) | F3NTRK1F2NTRK3 | |
| SCHEMBL30765747 | 0.82 | ELANE (0.39) | ELANE | |
| SCHEMBL30765595 | 0.82 | F3 (0.35) | F3F2CMA1CTRCPRSS1 | |
| SCHEMBL30765565 | 0.81 | F3 (0.36) | F3NTRK1F2CMA1CTRC | |
| SCHEMBL30766054 | 0.78 | ELANE (0.37) | F2ELANE | |
| SCHEMBL30765551 | 0.78 | F3 (0.41) | F3NTRK1F2CMA1CTRC | |
| SCHEMBL30765924 | 0.78 | GAA (0.45) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |