SCHEMBL30765781

SCHEMBL30765781

C[C@@H](Nc1cnc(N2CCCCC2)n(CC(=O)NCc2cc3cnccc3[nH]2)c1=O)c1coc(-c2ccccc2F)n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.33
MAPK1 P28482 1/20 0.33
F3 P13726 3/20 0.32
TRPV1 Q8NER1 1/20 0.30
NAMPT P43490 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765657 0.86 F2 (0.36) F2MAPK1F3TRPV1NAMPT
SCHEMBL30765880 0.85 F3 (0.36) F2F3
SCHEMBL30765486 0.84 NTRK1 (0.33)
SCHEMBL30765435 0.83 F2 (0.36) F2MAPK1F3NAMPTTSHR
SCHEMBL30765827 0.83 AKT1 (0.36) TSHR
SCHEMBL30765713 0.83 AKT1 (0.36) TSHR
SCHEMBL30765553 0.82 MAPK1 (0.37) F2MAPK1F3NAMPT
SCHEMBL30765646 0.80 MAPK1 (0.38) F2MAPK1F3NAMPT
SCHEMBL30766040 0.79 F2 (0.36) F2MAPK1F3TRPV1NAMPT
SCHEMBL30766059 0.79 ALDH1A1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 WO disclosed