Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765920 | 0.86 | L3MBTL1 (0.41) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765521 | 0.86 | KMT2A (0.38) | LMNAKMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL30765468 | 0.86 | LMNA (0.40) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30766075 | 0.85 | HDAC6 (0.42) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765802 | 0.84 | GAA (0.40) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765801 | 0.82 | LMNA (0.41) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765758 | 0.80 | L3MBTL1 (0.40) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765510 | 0.80 | L3MBTL1 (0.41) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765675 | 0.79 | L3MBTL1 (0.40) | LMNAKMT2AL3MBTL1GAAMAPT | |
| SCHEMBL30765977 | 0.79 | GAA (0.51) | LMNAKMT2AL3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |