Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765466 | 0.83 | DGAT2 (0.47) | DGAT2CASP1EGLN1CMA1CTRC | |
| SCHEMBL30765582 | 0.81 | KDM4C (0.42) | NTRK1KDM4ETSHRMTNR1BALDH1A1 | |
| SCHEMBL30765506 | 0.77 | NTRK1 (0.51) | NTRK1CMA1CTRCNTRK3 | |
| SCHEMBL30765708 | 0.77 | NTRK1 (0.39) | NTRK1CASP1MTNR1BELANENTRK3 | |
| SCHEMBL30765816 | 0.76 | NTRK1 (0.38) | DGAT2NTRK1LMNANTRK3 | |
| SCHEMBL30765889 | 0.74 | ELANE (0.38) | DGAT2NTRK1CASP1CMA1CTRC | |
| SCHEMBL30765443 | 0.73 | ELANE (0.39) | DGAT2NTRK1CASP1EGLN1CMA1 | |
| SCHEMBL30765590 | 0.72 | ELANE (0.45) | DGAT2CASP1ELANE | |
| SCHEMBL30765718 | 0.71 | NTRK1 (0.45) | NTRK1CMA1CTRCMTNR1BNTRK3 | |
| SCHEMBL30766024 | 0.71 | PDE4B (0.44) | CASP1CMA1PDE4BELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |